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What is Botox used for?

The Clostridium botulinum is a bacterium that produces spores that survive in improperly preserved or canned food. When eaten, even tiny amounts of this toxin can cause severe poisoning. Botulism may also occur if the organism enters at open wounds and produces the toxin at the inside. Despite of its dangerous effect on the human body, it is used in very low quantities to produce the cosmetic product called Botox. It is used mainly for cosmetically removing wrinkles and other uses include treating certain muscular conditions.

You can find botulinum toxin under these commercial names:
Botox (the most known name), Botox cosmetic (botulinum toxin type A or OnabotulinumtoxinA) or Vistabel
Dysport (botulinum toxin type A or AbobotulinumtoxinA)
Bocouture, Xeomin (botulinum toxin type A or IncobotulinumtoxinA)
Myobloc (botulinum toxin type B or IncobotulinumtoxinB)

Facts about Botox, a quick list.

This is a quick summary about Botox facts.

– Botox has become the most popular cosmetic treatment, reaching more than six million treatments administered along the year.
– It is a neurotoxin produced by Clostridum botulinum, this organism is found in natural environments where it is non-toxic and inactive.
– Botulinum toxin paralyzes the underlying muscles and then it reduces fine lines and wrinkles.
– Its medical uses include treatment of excessive sweating, muscular disorders, migraines, and some bladder and bowel disorders.
– If it is present into the human body at higher quantities it produces botulism, it is an infection that causes respiratory insufficiency which can result in death.
– Botulinum is so very toxic than just one gram could kill over a million people. Two kilograms could kill the entire humanity.

The Origin of Botox.

Clostridium botulinum, the bacterium from which Botox is produced, is present in nature in an inactive form, including forests and cultivated soils, at the lakes bottom inside the sediments, at streams, coastal and untreated waters.

It can also be found in the intestinal tracts of fish and mammals, in the gills and viscera of crabs and other shellfish. If Clostridium botulinum bacteria and spores occur at this natural instances are relatively harmless. The problem arises when the spores change in vegetative cells and their population increases at some point from where the bacteria start the production of botulinum toxin, and this is the deadly neurotoxin which is responsible of botulism.
The botulinum toxin (abbreviated either as BTX or BoNT) has eight subdivision types: A, B, C [C1,C2],D, E, F, G 18 and H.
From these types, A, B, E and in some cases F, cause botulism in humans, while chained types cause illness in other living beings like mammals, fish and birds.
Type G is apparently non dangerous because although it has been isolated from soil in Argentina, there is no evidence of any outbreak due to it.

After this event, researchers from the Centers for Disease Control and Prevention (CDC) and from the University of Wisconsin (UW) published a paper in the Journal of Infectious Diseases (JID) reporting that the toxin can be blocked by antitoxins already in use since the type H may not be a novel toxin.

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